Cardio IQ Advanced Lipid Panel

What is Cardio IQ and how does it work?

Cardio IQ is an advanced lipid panel that provides detailed insights into cardiovascular health by measuring cholesterol levels, triglycerides, and other key markers. This test helps assess the risk of heart disease and provides valuable information for personalized treatment and lifestyle modifications.

The Cardio IQ® Report provides an in-depth assessment of cardiovascular risks to help physicians recommend the ideal individualized treatment option for patients to minimize cardiovascular disease.

The report is simple, yet comprehensive. It is color-coded to display progressive risk values versus goal using “optimal,” “moderate,” and “high-risk” categories and grouped by functional categories.

Cardio IQ Advanced Lipid Panel The Cardio IQ Advanced Lipid Panel includes:Total Cholesterol, Triglycerides, HDL, LDL and Cholesterol/HDL ratio, LDL Particle Number, LDL Peak Size, LDL Pattern, HDL Large, LDL Small, LDL Medium, Apolipoprotein B, Lipoprotein (a). FASTING REQUIRED. Results for this test take 2 weeks to receive.

What Does the Cardio IQ Advanced Lipid Panel Measure?

The Cardio IQ Advanced Lipid Panel includes:

• Total Cholesterol, Triglycerides, HDL, LDL and Cholesterol/HDL ratio
• LDL Particle Number (LDL-P): LDL-P counts the number of low-density lipoprotein (LDL) particles in the blood. Each LDL particle carries cholesterol and triglycerides to tissues all over the body. Studies have shown that a higher LDL-P count is a better indicator of heart disease risk than LDL cholesterol (LDL-C) alone. This is because a high LDL-P count means that there are more particles that cause plaque to form in the bloodstream.
• LDL Peak Size: The LDL peak size is how the size of LDL particles in the blood is spread out. Based on their size, LDL particles can be put into two main groups: small, dense LDL particles (sdLDL) and large, buoyant LDL particles. Smaller, denser LDL particles are thought to be more atherogenic because they can get deeper into arterial walls, are more likely to oxidize, and have less of a pull on LDL receptors. So, a smaller LDL peak size is linked to an increased risk of heart disease.
• LDL Pattern: The LDL pattern is the type of LDL particles that are most common in the blood, either Pattern A (large, buoyant LDL particles) or Pattern B (small, dense LDL particles). Small, dense LDL particles cause atherosclerosis, which means that people with Pattern B are more likely to have heart disease.
• HDL Large: HDL Large is a subclass of high-density lipoprotein (HDL) particles that are bigger. Large HDL particles are thought to protect the heart because they are better at removing cholesterol from cells (cholesterol efflux) and moving cholesterol away from cells (reverse cholesterol transport) (transporting cholesterol from peripheral tissues back to the liver for excretion). Heart disease is less likely to happen if you have a lot of large HDL particles in your blood.
• LDL Small: LDL small means small, dense LDL particles, which are more likely to cause atherosclerosis than large, buoyant LDL particles. High levels of small LDL particles are linked to a higher risk of cardiovascular disease because they can get into arterial walls more easily and cause plaque to form.
• LDL Medium: The LDL particles that are in between the small, dense LDL and the big, floaty LDL are called LDL medium. When compared to the other two subclasses, these particles have a middle level of atherogenic potential. Less is known about the clinical importance of medium-sized LDL particles, but it is important to think about them as a part of the whole LDL particle profile.
• Apolipoprotein B (ApoB): ApoB is the main protein in all atherogenic lipoproteins, like LDL, VLDL, and IDL (IDL). One ApoB molecule is in each atherogenic particle. By measuring ApoB levels, you can get an idea of how many atherogenic particles are in your blood. Heart disease is more likely to happen if you have a high level of ApoB.
• Lipoprotein (a) (Lp(a)) is a lipoprotein that has the same structure as LDL, but Apo(a) is attached to ApoB instead of ApoB alone. Lp(a) makes atherosclerosis worse by making plaques and slowing down fibrinolysis (the breakdown of blood clots). High Lp(a) levels on their own are a risk factor for cardiovascular disease, and genes primarily contribute to this risk.

By looking at these lipid markers, doctors can get a better idea of a patient's risk for cardiovascular disease and make treatment plans that focus on specific lipid abnormalities. This all-around approach could help lower the overall risk of getting heart disease.

How Long Does It Take to Get Cardio IQ Panel Results?

Results for this test take 2 weeks to receive.

How to Prepare for the Cardio IQ Test

It is recommended to fast for 12–14 hours before getting your blood drawn for this test.

Why is Cardio IQ Advanced Lipid Panel More Useful Than a Simple Lipid Panel?

The Cardio IQ® Report provides an in-depth assessment of cardiovascular risks to help physicians recommend the ideal individualized treatment option for patients to minimize cardiovascular disease.

The report is simple yet comprehensive. It is color-coded to display progressive risk values versus goals using “optimal,” “moderate,” and “high-risk” categories and grouped by functional categories.

This advanced test uses a technology called ion mobility, specifically the Cardio IQ Lipoprotein Fractionation test from Quest Diagnostics. This test goes far beyond your basic lipid test and replaces the VAP® Cholesterol Test. For starters, this test helps to reclassify a patient’s cardiovascular risk, making it more useful than a simple lipid panel for healthcare providers in evaluating a broader range of cardiovascular risks, including the risk of heart attack and stroke, overall cholesterol levels, and blood pressure. However, the Cardio IQ Advanced Lipid Panel is not just useful for evaluating cardiovascular risk, but also for assessing overall health through a comprehensive test panel. While routine lipid profiles only measure cholesterol levels, this advanced test also evaluates other factors such as inflammation and insulin resistance, providing detailed information and a more complete understanding of a patient's overall health, including potential risks for liver disease. Additionally, the advanced lipid testing in Cardio IQ can also help patients make informed decisions about their overall wellness by leveraging topics such as fasting before testing, reclassification of patient risk profiles, monitoring lifestyle changes with repeat tests, and medication management based on test results.

With its advanced technology and comprehensive analysis, Cardio IQ Advanced Lipid Panel, which includes additional blood biomarkers such as the Apolipoprotein B test, is the best heart disease predictor available. Furthermore, regular Cardio IQ Advanced Lipid Panel testing can also help healthcare providers track the impact of dietary changes on cholesterol levels and make necessary adjustments to achieve optimal levels for their patients. Additionally, according to a major study, half of all patients hospitalized for cardiovascular disease have "normal" cholesterol levels, making the advanced lipid panel even more crucial for accurate risk assessment and management. Special Notes: Fasting is required 9–12 hours prior to giving blood sample. Tests Included: Cardio IQ® Advanced Lipid Panel, including the Cardio IQ® Direct LDL test. Payment can be completed using a credit card or other available options.

Very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) particles are all part of the lipoprotein spectrum that can be precisely measured using ion mobility technology. Ion mobility identifies 2 main subclasses of HDL: large HDL and small HDL. The antioxidant properties of large HDL may help protect the arterial wall from the buildup of LDL cholesterol, also known as bad cholesterol. A decreased large HDL subclass has historically suggested increased CVD risk, including heart risks such as heart attack. The Cardio IQ Advanced Lipid Panel gives a more complete picture of a person's heart health than a standard lipid profile because it measures all lipoprotein fractions, including those that can build up on artery walls. It does this by measuring levels of good cholesterol (HDL) and bad cholesterol (LDL), as well as other important markers like HDL cholesterol.

An elevated total LDL particle number is associated with a 1.2 to 1.4-fold increase in cardiovascular disease risk. Similarly, elevated small and medium LDL particle numbers have been associated with a 1.2 to 1.4-fold increase.

What to Do to Improve Cardio IQ Advanced Lipid Panel Abnormal Results?

The following table shows what to do when any of the lab test results shown by your Cardio IQ test is abnormal.

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